In this tutorial, FABIAN-variant is used to analyze variants from a whole genome sequencing (WGS) run using transcription factor flexible models (TFFMs).
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26.05.2022 · FABIAN-variant is available freely at https://www.genecascade.org/fabian/. ... Links to the documentation and a tutorial are provided on the ...
PDF | While great advances in predicting the effects of coding variants have been made, the assessment of non-coding variants remains challenging. This.
Background: The modelling of gene regulation is a major challenge in biomedical research. This process is dominated by transcription factors (TFs) and mutations ...
09.06.2022 · Genetic factors are relevant for both eating disorders and body weight regulation. A recent genome-wide association study (GWAS) for ...
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01.07.2022 · This is the 20th edition of the Nucleic Acids Research Web Server Issue. Under normal circumstances, this would be an opportunity to ...
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To this end, FABIAN-variant tool from GeneCascade. (https://www.genecascade.org/fabian/) was used (CITE). This tool estimates the impact of a variant on CTCF ...
17.10.2016 · This construct, introduced along with the guide RNA and Cas9 expression vector, is analogous to the homologous recombination constructs ...